Quality evaluation of the cinnamon essential oils based on gas chromatographic analysis and cytotoxicity = 가스 크로마토그래피 분석과 세포독성에 의한 계피 정유의 품질평가

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Title
Quality evaluation of the cinnamon essential oils based on gas chromatographic analysis and cytotoxicity = 가스 크로마토그래피 분석과 세포독성에 의한 계피 정유의 품질평가
Author(s)
H J Park; H J Jung; W T Jung; J Choi; J H Nam; K T Lee; Byoung-Mog Kwon
Bibliographic Citation
Korean Journal of Pharmacognosy, vol. 35, no. 4, pp. 288-292
Publication Year
2004
Abstract
To evaluate the quality of the crude drugs using three kinds of Cinnamomum Cortex (CC), Vietnamese CC (VCC, the stem bark of Cinnamomum obtusifolium), periderm-peeled Chinese CC (PPCC, periderm-peeled stem bark of C. cassia), Chinese CC (CCC, stem bark of C. cassia) and a Cinnamomi Ramulus (CR, the twig of C. cassia), the four essential oils were prepared by steam distillation method. Cinnamaldehdye (CNA) and an unknown substance tentatively named hydroxycinnamaldehdye (HCNA) were detected in the four essential oils by gas chromatography-mass spectrometry, the contents of which are significantly different one another. Vietnamese CC had the highest content of HCNA whereas CR had the highest CNA content and the lowest HCNA. Vietnamese CC exhibited the greatest cytotoxic activity against the cancer cell lines, A549, HepG-2, HL-60, P-388, U-937, and KB and CR the lowest cytotoxicity. Contents of CNA and HCNA in CCC and PPCC are positioned between VCC and CR. These results suggest that measurement of HCNA and cytotoxicity may determine the quality of CC and CR.
Keyword
cinnamaldehydecinnamomumcytotoxicityGC-MShydroxycinnamaldehydequality evaluation
ISSN
0253-3073
Publisher
Korea Soc-Assoc-Inst
Type
Article
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1. Journal Articles > Journal Articles
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