Varied patterns of DNA methylation change between different satellite regions in bovine preimplantation development

Cited 27 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorYong-Kook Kang-
dc.contributor.authorH J Lee-
dc.contributor.authorJung Jae Shim-
dc.contributor.authorSeungEun Yeo-
dc.contributor.authorSeok Ho Kim-
dc.contributor.authorDeog Bon Koo-
dc.contributor.authorKyung Kwang Lee-
dc.contributor.authorZ Beyhan-
dc.contributor.authorN L First-
dc.contributor.authorYong Mahn Han-
dc.date.accessioned2017-04-19T09:02:32Z-
dc.date.available2017-04-19T09:02:32Z-
dc.date.issued2005-
dc.identifier.issn1040-452X-
dc.identifier.uri10.1002/mrd.20249ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/6860-
dc.description.abstractGlobal reduction of DNA methylation, a part of genome reprogramming processes, occurs in a gradual manner until before implantation and is recognized as a conserved process in mammals. Here, we reported that in bovine, satellite regions exhibited varied patterns of methylation changes when one-cell egg advanced to the blastocyst; a maintenance methylation was observed in satellite I sequences, a decrease in alpha satellites, and an increase in satellite II regions. Cloned embryos exhibited similar changes for DNA methylation in the satellite I and alpha. We also observed that the satellite I and α sequences were methylated more in inner cell mass region of the blastocyst whereas the satellite II showed selective demethylation in this region. Together, these findings point that individual satellite sequences carry their own methylation patterns under the pressure of global demethylation, suggesting that local methylation control system acts on the satellite regions in early bovine embryos.-
dc.publisherWiley-
dc.titleVaried patterns of DNA methylation change between different satellite regions in bovine preimplantation development-
dc.title.alternativeVaried patterns of DNA methylation change between different satellite regions in bovine preimplantation development-
dc.typeArticle-
dc.citation.titleMolecular Reproduction and Development-
dc.citation.number1-
dc.citation.endPage35-
dc.citation.startPage29-
dc.citation.volume71-
dc.contributor.affiliatedAuthorYong-Kook Kang-
dc.contributor.affiliatedAuthorJung Jae Shim-
dc.contributor.affiliatedAuthorSeungEun Yeo-
dc.contributor.affiliatedAuthorSeok Ho Kim-
dc.contributor.affiliatedAuthorDeog Bon Koo-
dc.contributor.affiliatedAuthorKyung Kwang Lee-
dc.contributor.affiliatedAuthorYong Mahn Han-
dc.contributor.alternativeName강용국-
dc.contributor.alternativeName이효종-
dc.contributor.alternativeName심정재-
dc.contributor.alternativeName여승은-
dc.contributor.alternativeName김석호-
dc.contributor.alternativeName구덕본-
dc.contributor.alternativeName이경광-
dc.contributor.alternativeNameBeyhan-
dc.contributor.alternativeNameFirst-
dc.contributor.alternativeName한용만-
dc.identifier.bibliographicCitationMolecular Reproduction and Development, vol. 71, no. 1, pp. 29-35-
dc.identifier.doi10.1002/mrd.20249-
dc.subject.keywordbovine-
dc.subject.keyworddemethylation-
dc.subject.keywordDNA methylation-
dc.subject.keywordpreimplantation embryo-
dc.subject.keywordsatellite sequences-
dc.subject.localBovine-
dc.subject.localbovine-
dc.subject.localdemethylation-
dc.subject.localDemethylation-
dc.subject.localDNA methylation-
dc.subject.localDNAmethylation-
dc.subject.localpreimplantation embryo-
dc.subject.localPre-implantation embryos-
dc.subject.localPreimplantation embryo-
dc.subject.localsatellite sequences-
dc.description.journalClassY-
Appears in Collections:
Aging Convergence Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.