DC Field | Value | Language |
---|---|---|
dc.contributor.author | N T Dat | - |
dc.contributor.author | X F Cai | - |
dc.contributor.author | Mun Chual Rho | - |
dc.contributor.author | Hyun Sun Lee | - |
dc.contributor.author | K Bae | - |
dc.contributor.author | Y H Kim | - |
dc.date.accessioned | 2017-04-19T09:02:34Z | - |
dc.date.available | 2017-04-19T09:02:34Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6870 | - |
dc.description.abstract | The EtOAc extract of Youngia koidzumiana significantly inhibited the diacylglycerol acyltrans-ferase (DGAT) from rat liver microsomes. Bioactivity-guided fractionation led to the isolation of nine compounds, the structures of which were established using physicochemical and spectral data. of the isolated compounds, oleanolic acid (2), methyl ursolate (7) and corosolic aicd (8) inhibited DGAT, with IC50 values of 31.7, 26.4, and 44.3 μM, respectively. However, sesquiterpenoids showed only weak inhibitory effects toward DGAT. | - |
dc.publisher | Pharmaceutical Soc Korea | - |
dc.title | The inhibition of diacylglycerol acyltransferase by terpenoids from Youngia koidzumiana | - |
dc.title.alternative | The inhibition of diacylglycerol acyltransferase by terpenoids from Youngia koidzumiana | - |
dc.type | Article | - |
dc.citation.title | Archives of Pharmacal Research | - |
dc.citation.number | 2 | - |
dc.citation.endPage | 168 | - |
dc.citation.startPage | 164 | - |
dc.citation.volume | 28 | - |
dc.contributor.affiliatedAuthor | Mun Chual Rho | - |
dc.contributor.affiliatedAuthor | Hyun Sun Lee | - |
dc.contributor.alternativeName | Dat | - |
dc.contributor.alternativeName | Cai | - |
dc.contributor.alternativeName | 노문철 | - |
dc.contributor.alternativeName | 이현선 | - |
dc.contributor.alternativeName | 배기환 | - |
dc.contributor.alternativeName | 김영호 | - |
dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 28, no. 2, pp. 164-168 | - |
dc.identifier.doi | 10.1007/bf02977708 | - |
dc.subject.keyword | brachynereolide | - |
dc.subject.keyword | corosolic acid | - |
dc.subject.keyword | crepidiaside C | - |
dc.subject.keyword | diacylglycerol acyltransferase | - |
dc.subject.keyword | germanicol acetate | - |
dc.subject.keyword | ixerin Y | - |
dc.subject.keyword | methyl ursolate | - |
dc.subject.keyword | youngia koidzumiana | - |
dc.subject.local | brachynereolide | - |
dc.subject.local | Corosolic acid | - |
dc.subject.local | corosolic acid | - |
dc.subject.local | crepidiaside C | - |
dc.subject.local | diacylglycerol acyltransferase | - |
dc.subject.local | diacylglycerol acyltansferase (DGAT) | - |
dc.subject.local | Diacylglycerol acyltransferase | - |
dc.subject.local | Diacylglycerol acyltransferase (DGAT) | - |
dc.subject.local | germanicol acetate | - |
dc.subject.local | ixerin Y | - |
dc.subject.local | methyl ursolate | - |
dc.subject.local | Youngia koidzumiana | - |
dc.subject.local | youngia koidzumiana | - |
dc.description.journalClass | Y | - |
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