Inhibitory activity of isorhamnetin from Persicaria thunbergii on farnesyl protein transferase
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hyun Mi Oh | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | N I Baek | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | I S Chung | - |
| dc.contributor.author | M H Park | - |
| dc.contributor.author | H W Park | - |
| dc.contributor.author | J H Lee | - |
| dc.contributor.author | H W Park | - |
| dc.contributor.author | E J Kim | - |
| dc.contributor.author | D K Kim | - |
| dc.date.accessioned | 2017-04-19T09:02:34Z | - |
| dc.date.available | 2017-04-19T09:02:34Z | - |
| dc.date.issued | 2005 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | 10.1007/BF02977709 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/6871 | - |
| dc.description.abstract | The methanolic extract of the aerial parts of Persicaria thunbergii was found to show inhibitory activity on Farnesyl Protein Transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of isorhamnetin, as an inhibitor on FPTase. This compound inhibited FPTase activity in a dose-dependent manner, and the IC50 value of isorhamnetin was 37.5 μM. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Inhibitory activity of isorhamnetin from Persicaria thunbergii on farnesyl protein transferase | - |
| dc.title.alternative | Inhibitory activity of isorhamnetin from Persicaria thunbergii on farnesyl protein transferase | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 2 | - |
| dc.citation.endPage | 171 | - |
| dc.citation.startPage | 169 | - |
| dc.citation.volume | 28 | - |
| dc.contributor.affiliatedAuthor | Hyun Mi Oh | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.alternativeName | 오현미 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.contributor.alternativeName | 김성훈 | - |
| dc.contributor.alternativeName | 정인식 | - |
| dc.contributor.alternativeName | 박미현 | - |
| dc.contributor.alternativeName | 박희욱 | - |
| dc.contributor.alternativeName | 이재혁 | - |
| dc.contributor.alternativeName | 박혜원 | - |
| dc.contributor.alternativeName | 김은정 | - |
| dc.contributor.alternativeName | 김대근 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 28, no. 2, pp. 169-171 | - |
| dc.identifier.doi | 10.1007/BF02977709 | - |
| dc.subject.keyword | FPTase | - |
| dc.subject.keyword | Isorhamnetin | - |
| dc.subject.keyword | Persicaria thunbergii | - |
| dc.subject.local | FPTase | - |
| dc.subject.local | Isorhamnetin | - |
| dc.subject.local | isorhamnetin | - |
| dc.subject.local | Persicaria thunbergii | - |
| dc.subject.local | persicaria thunbergii | - |
| dc.description.journalClass | Y | - |
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