Stereochemistry of phellinsin A: a concise synthesis of α-arylidene-γ-lactones
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Title
Stereochemistry of phellinsin A: a concise synthesis of α-arylidene-γ-lactones
Author(s)
EungSoo Kim; Hyeong Kyu Lee; Eui Il Hwang; Sung Uk Kim; Woo Song Lee; Sangku Lee; S H Jung
Bibliographic Citation
Synthetic Communications, vol. 35, no. 9, pp. 1231-1238
Publication Year
2005
Abstract
Phellinsin A (1a) was prepared in a concise way, thereby elucidating the relative stereochemistry of the aryl and carboxylic acid groups in 1a. The synthesis employed selective monohydrolysis of the dilactones derived from oxidative dimerization of cinnamic acid derivatives. This approach provided a practical synthetic route to α-arylidene-γ-lactones.