The Bombyx mori gene wds codes for a WD-repeat protein with seven repeats

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Title
The Bombyx mori gene wds codes for a WD-repeat protein with seven repeats
Author(s)
K A Kim; S M Hong; Nam-Soon Kim; J S Lee; S W Kang; S K Nho
Bibliographic Citation
Genes & Genomics, vol. 27, no. 2, pp. 145-151
Publication Year
2005
Abstract
We isolated and characterized the wds gene of Bombyx mori. The gene codes for 1,431 bp RNA that is transcribed at embryogenesis and at all stages of development. The transcript products were at a high level in early embryogenesis and gradually declined. The level of wds transcripts in the germ cells are high in comparison with other tissue. The RNA has been localized by an in situ hybridization sperm packet, spermatogonia and spermatocytes in the testis. The putative translation product contains seven WD-repeats and is, therefore, a member of the family of WD-protein. Clear homologues of the B. mori WDS protein exist in three other fully sequenced higher eukaryotes- human, the insect Drosophila melanogaster and Anopheles gambiae.
Keyword
bombyx moriembryogenesiseukaryotesgerm cellsWD-repeat
ISSN
1976-9571
Publisher
Springer
Type
Article
Appears in Collections:
Division of Biomedical Research > Rare Disease Research Center > 1. Journal Articles
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