A glycosidic isoflavonoid from Viola hondoensis W. Becker et H. Boissieu (violaceae), and its effect on the expression of matrix metalloproteinase-1 caused by ultraviolet irradiation in cultured human skin fibroblasts

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Title
A glycosidic isoflavonoid from Viola hondoensis W. Becker et H. Boissieu (violaceae), and its effect on the expression of matrix metalloproteinase-1 caused by ultraviolet irradiation in cultured human skin fibroblasts
Author(s)
H I Moon; Joongku Lee; O P Zee; J H Chung
Bibliographic Citation
Biological & Pharmaceutical Bulletin, vol. 28, no. 6, pp. 1123-1125
Publication Year
2005
Abstract
Isolation of the ethyl acetate soluble fraction from aerial parts of Viola hondoensis W. BECKER et H. BOISSIEU yielded one major isoflavonoid glycoside, tectoridin-4′-O-β-D-glucoside. The structure of the compound was certainly determined by chemical analyses, as well as 1D- and 2D-NMR spectroscopy. The compound exhibited potent inhibitory activity against the expression of matrix metalloproteinase-1 caused by UV-irradiation in cultured human skin fibroblasts.
Keyword
Viola hondoensistectoridin-4 -O-b -D-glucosidematrix metalloproteinasehuman skin fibroblasts
ISSN
0918-6158
Publisher
Pharmaceutical Soc Japan
DOI
http://dx.doi.org/10.1248/bpb.28.1123
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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