Coumarins and chromones from Angelica genuflexa

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dc.contributor.authorRen Bo An-
dc.contributor.authorBo Young Park-
dc.contributor.authorJung Hee Kim-
dc.contributor.authorOk Kyoung Kwon-
dc.contributor.authorJoongku Lee-
dc.contributor.authorByung Sun Min-
dc.contributor.authorKyung Seop Ahn-
dc.contributor.authorSei Ryang Oh-
dc.contributor.authorHyeong Kyu Lee-
dc.date.accessioned2017-04-19T09:03:09Z-
dc.date.available2017-04-19T09:03:09Z-
dc.date.issued2005-
dc.identifier.issnI0000147-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7039-
dc.description.abstractThirteen compounds were isolated from the roots of Angelica genuflexa through repeated silica gel column chromatography. Nine coumarins, isoimperatorin (1), osthol (2), demethylsuberosin (3), oxypeucedanin (4), heraclenin (5), pabulenol (7), umbelliferone (8), oxypeucedanin hydrate (9) and marmesinin (11), and four chromones, hamaudol (6), cimifugin (10), sec-O-glucosylhamaudol (12) and prim-O-glucosylcimifugin (13), were identified by physicochemical and spectroscopic analysis. Among these, compounds 3, 5, 6, 8, 12, and 13 were isolated for the first time from the roots of Angelica genuflexa. These coumarins and chromones were examined for their anticomplement activity. Demethylsuberosin (3) showed a weak anticomplement activity with an IC50 value of 390 μM.-
dc.publisherKorean Society of Pharmacognosyko
dc.titleCoumarins and chromones from Angelica genuflexa-
dc.title.alternativeCoumarins and chromones from Angelica genuflexa-
dc.typeArticle-
dc.citation.titleNatural Products Sciences-
dc.citation.number2-
dc.citation.endPage84-
dc.citation.startPage79-
dc.citation.volume11-
dc.contributor.affiliatedAuthorJung Hee Kim-
dc.contributor.affiliatedAuthorOk Kyoung Kwon-
dc.contributor.affiliatedAuthorKyung Seop Ahn-
dc.contributor.affiliatedAuthorSei Ryang Oh-
dc.contributor.alternativeName안인파-
dc.contributor.alternativeName박보영-
dc.contributor.alternativeName김정희-
dc.contributor.alternativeName권옥경-
dc.contributor.alternativeName이중구-
dc.contributor.alternativeName민병선-
dc.contributor.alternativeName안경섭-
dc.contributor.alternativeName오세량-
dc.contributor.alternativeName이형규-
dc.identifier.bibliographicCitationNatural Products Sciences, vol. 11, no. 2, pp. 79-84-
dc.subject.keywordangelica genuflexa-
dc.subject.keywordanticomplement activity-
dc.subject.keyworddemethylsuberosin-
dc.subject.keywordhamaudol-
dc.subject.keywordheraclenin-
dc.subject.keywordprim-O-glucosylcimifugin-
dc.subject.keywordsec-O-glucosylhamaudol-
dc.subject.keywordumbelliferone-
dc.subject.localangelica genuflexa-
dc.subject.localanticomplement activity-
dc.subject.localAnticomplement activity-
dc.subject.localdemethylsuberosin-
dc.subject.localhamaudol-
dc.subject.localheraclenin-
dc.subject.localprim-O-glucosylcimifugin-
dc.subject.localsec-O-glucosylhamaudol-
dc.subject.localumbelliferone-
dc.description.journalClassN-
Appears in Collections:
Ochang Branch Institute > Natural Medicine Research Center > 1. Journal Articles
Ochang Branch Institute > 1. Journal Articles
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