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- Title
- A combined approach for locating Box H/ACA snoRNAs in the human genome
- Author(s)
- H S Eo; K S Jo; S W Lee; Chang-Bae Kim; W Kim
- Bibliographic Citation
- Molecules and Cells, vol. 20, no. 1, pp. 35-42
- Publication Year
- 2005
- Abstract
- A novel combined method for locating box H/ACA small nucleolar RNAs (snoRNAs) is described, together with a software tool. The method adopts both a probabilistic hidden Markov model (HMM) and a minimum free energy (MFE) rule, and filters possible candidate box H/ACA snoRNAs obtained from genomic DNA sequences. With our novel method 12 known box H/ACA snoRNAs, and one strong candidate were identified in 30 nucleolar protein genomic sequences.
- Keyword
- hidden markov modelminimum free energyBox H/ACA snoRNA
- ISSN
- 1016-8478
- Publisher
- Korea Soc-Assoc-Inst
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
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