A practical enzymatic synthesis of UDP sugars and NDP glucoses
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- Title
- A practical enzymatic synthesis of UDP sugars and NDP glucoses
- Author(s)
- JungDon Bae; Kwang Ho Kim; DooIl Kim; Yongseok Choi; Joong Su Kim; Sukhoon Koh; S I Hong; Dae Sil Lee
- Bibliographic Citation
- Chembiochem, vol. 6, no. 11, pp. 1963-1966
- Publication Year
- 2005
- Abstract
- Mix and match. Nucleotide sugars are essential as glycoside donors to glycosyltransferases for the synthesis of bioactive metabolites. With 45 combinations of reactions with five NTPs and nine sugar-1-phosphates (Su1Ps) by recombinant UDP-sugar pyrophosphorylase (Up) from Thermus caldophilus GK24, the enzyme showed broad substrate specificity toward five types of NTP with glucose-1-phosphate as well as four Su1Ps with UTP, affording all nine nucleotide sugars.
- ISSN
- 1439-4227
- Publisher
- Wiley
- Full Text Link
- http://dx.doi.org/10.1002/cbic.200500183
- Type
- Article
- Appears in Collections:
- Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
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