Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-Oxidation

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Title
Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-Oxidation
Author(s)
D H Kim; H J Lee; Y J Oh; Min Jung Kim; S H Kim; Tae Sook Jeong; N I Baek
Bibliographic Citation
Archives of Pharmacal Research, vol. 28, no. 10, pp. 1156-1160
Publication Year
2005
Abstract
An iridoid glycoside, oldenlandoside III (5) was isolated from the n-butanol fraction of methanol extracts of the aerial parts of Oldenlandia diffusa Roxb. along with six others previously characterized iridoid glycosides; geniposidic acid (1), scandoside (2), feretoside (3), 10-O-benzoylscandoside methyl ester (4), asperulosidic acid (6) and deacetylasperulosidic acid (7). Compounds 1, 2, and 7 inhibited LDL-oxidation, and showed 63.3±2.0, 62.2±1.6, and 63.8±1.5% inhibition, respectively, at a concentration of 20 μg/mL.
Keyword
iridoidLDL-Oxidation inhibitionoldenlandia diffusaoldenlandoside IIIrubiaceae
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/BF02972979
Type
Article
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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