Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea
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- Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea
- Y C Chung; Hyo Kon Chun; Jae Young Yang; J Y Kim; E H Han; Yung Hee Kho; H G Jeong
- Bibliographic Citation
- Archives of Pharmacal Research, vol. 28, no. 10, pp. 1122-1126
- Publication Year
- Tungtungmadic acid (3-caffeoyl-4-dihydrocaffeoyl quinic acid) is a new chlorogenic acid derivative that was isolated from the Salicornia herbacea. The structure of tungtungmadic acid was determined using chemical and spectral analysis. The antioxidant activity of tungtungmadic acid was evaluated using various antioxidant assays, including free radical scavenging, lipid peroxidation and hydroxyl radical-induced DNA strand breaks assays. Tungtungmadic acid (IC50 = 5.1 μM and 9.3 μM) was found to have higher antioxidant activity in the DPPH scavenging assay as well as in the iron-induced liver microsomal lipid peroxidation system. In addition, the tungtungmadic acid was also effective in protecting the plasmid DNA against strand breakage induced by hydroxyl radicals.
- 3-caffeoyl-4-dihydrocaffeoyl quinic acid; antioxidant activity; salicornia herbacea; tungtungmadic acid
- Pharmaceutical Soc Korea
- Appears in Collections:
- Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
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