Kitasatospora sp. MJM383 strain producing two antitumor agents, streptonigrin and oxopropaline G

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Title
Kitasatospora sp. MJM383 strain producing two antitumor agents, streptonigrin and oxopropaline G
Author(s)
Y Y Jin; T M Yoon; Won Gon Kim; K R Kim; J K Song; J G Kim; J Liu; Y Y Yang; H J Kwon; J W Suh
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 15, no. 5, pp. 1140-1145
Publication Year
2005
Abstract
MJM383, a rare actinomycete sp. strain originated from Chinese soils, was isolated through an antimicrobial screening system. The analysis of 16S rDNA sequences and biochemical characterization determined the strain to belong to genus Kitasatospora. Both NMR and ESI mass data of its purified bioactive compounds revealed Kitasatospora sp. MJM383 to produce two antitumor agents, streptonigrin and oxopropaline G, which have been known to be produced from Streptomyces species. This is the first report to demonstrate the presence of antitumor agents produced by genus Kitasatospora.
Keyword
rare actinomycetestreptonigrin16S rDNA sequencekitasatospora sp. MJM383oxopropaline
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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