A new variant of the mouse Akp1 locus

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Title
A new variant of the mouse Akp1 locus
Author(s)
Chul Ho Lee; Eun Hee Kim; Young Suk Won; Y K Choi; Ki Hoan NamHyoung-Chin Kim; Byung Hwa Hyun; J G Suh; Y S Oh
Bibliographic Citation
Biochemical Genetics, vol. 43, no. 11, pp. 597-602
Publication Year
2005
Abstract
A new electrophoretic migration type of alkaline phosphatase 1 (Akp1) was found on the cellulose acetate electrophoresis for kidney and liver homogenates of KWHM mouse, a newly established inbred strain derived from the Korean wild mouse (Mus musculus molossinus). This new type of alkaline phosphatase 1 was distinguished from previously reported AKP1A and AKP1B types in the mouse, and tentatively named AKP1C. In genetic analysis by mating experiments between KWHM and C57BL/6J (AKP1A) or BALB/cA (AKP1B), the phenotypic segregation ratios of AKP1A : AKP1AC : AKP1C or AKP1B : AKP1BC : AKP1C were 1 : 2 : 1 in both groups of F2 generations. It was therefore concluded that AKP1C type is controlled by Akp1c allele which is codominant with Akp1a and Akp1 b alleles.
Keyword
Alkaline phosphataseElectrophoresisMus musculus
ISSN
0006-2928
Publisher
Springer
DOI
http://dx.doi.org/10.1007/s10528-005-9116-5
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
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