Sung-Kyu Choi; H M Oh; Su-Kyung Lee; Dae Gwin Jeong; Seong Eon Ryu; Kwang Hee Son; Dong Cho Han; N D Sung; N I Baek; Byoung-Mog Kwon
Bibliographic Citation
Natural Product Research, vol. 20, no. 4, pp. 341-346
Publication Year
2006
Abstract
Two biflavonoids, ginkgetin (1) and sciadopitysin (2), were isolated from the MeOH extract of the young branches of Taxus cuspidata, which inhibited phosphatase of regenerating liver-3 (PRL-3) with IC50 values of 25.8 and 46.2 μM, respectively. This is the first report on PRL-3 inhibitors, isolated from natural sources.