Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3) = 바이플라보노이드의 PRL-3 저해활성

Cited 38 time in scopus
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Title
Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3) = 바이플라보노이드의 PRL-3 저해활성
Author(s)
Sung-Kyu Choi; H M Oh; Su-Kyung Lee; Dae Gwin Jeong; Seong Eon Ryu; Kwang Hee SonDong Cho Han; N D Sung; N I Baek; Byoung-Mog Kwon
Bibliographic Citation
Natural Product Research, vol. 20, no. 4, pp. 341-346
Publication Year
2006
Abstract
Two biflavonoids, ginkgetin (1) and sciadopitysin (2), were isolated from the MeOH extract of the young branches of Taxus cuspidata, which inhibited phosphatase of regenerating liver-3 (PRL-3) with IC50 values of 25.8 and 46.2 μM, respectively. This is the first report on PRL-3 inhibitors, isolated from natural sources.
Keyword
BiflavonoidsGinkgetinMetastasisPRL-3SciadopitysinTaxus cuspidata
ISSN
1029-2349
Publisher
T&F (Taylor & Francis)
DOI
http://dx.doi.org/10.1080/14786410500463312
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
Division of Biomedical Research > Personalized Genomic Medicine Research Center > 1. Journal Articles
Division of Biomedical Research > Genome Editing Research Center > 1. Journal Articles
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