Development of biologically active compounds from edible plant sources-XVII: isolation of sterols from the fruits of Cornus kousa Burg. = 식용식물자원으로부터 활성물질의 탐색-XVII: 산딸나무(Cornus kousa Burg.)의 열매로부터 sterol 화합물의 분리

Abstract

The fruits of Cornus kousa Burg. were extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH an H2O, successively. From the EtOAc fraction, three sterols were isolated through the repeated silica gel and ODS column chromatographies. According to the results of physico-chemical data including NMR, MS and IR, the chemical structures of compounds were determined as β-sitosterol (1), stigmast-4-en-6β-ol-3-one (2) and daucosterol (3). They were the first to be isolated from Cornus kousa Burg.