Two novel furan derivatives from Phellinus linteus with anti-complement activity = 항보체효과를 갖는 상황버섯의 퓨란화합물
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- Title
- Two novel furan derivatives from Phellinus linteus with anti-complement activity = 항보체효과를 갖는 상황버섯의 퓨란화합물
- Author(s)
- B S Min; Bong Sik Yun; Hyeong Kyu Lee; H J Jung; H A Jung; J S Choi
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 12, pp. 3255-3257
- Publication Year
- 2006
- Abstract
- Two novel stereoisomers of furan derivatives, phellinusfurans A (1) and B (2), were isolated from the fruiting body of Phellinus linteus. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 exhibited significant anti-complement activity with IC50 values of 33.6 and 33.7 μM, respectively, in inhibiting the hemolytic activity of human serum against erythrocytes.
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/j.bmcl.2006.03.027
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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