Antioxidant activities of abietane diterpenoids isolated from Torreya nucifera leaves

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dc.contributor.authorWoo Song Lee-
dc.contributor.authorJ R Kim-
dc.contributor.authorJong Min Han-
dc.contributor.authorK C Jang-
dc.contributor.authorD E Sok-
dc.contributor.authorTae Sook Jeong-
dc.date.accessioned2017-04-19T09:04:52Z-
dc.date.available2017-04-19T09:04:52Z-
dc.date.issued2006-
dc.identifier.issn0021-8561-
dc.identifier.uri10.1021/jf060896cko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7494-
dc.description.abstractInvestigation on antioxidant compounds from the ethanolic extracts of Torreya nucifera leaves resulted in the isolation of abietane diterpenoids, a known 18-methylesterferruginol (1) and a new 18-dimethoxyferruginol (2). The structures of compounds 1 and 2 were elucidated on the basis of their spectroscopic analyses. Compounds 1 and 2 inhibited the Cu2+- mediated, 2,2′-azobis(2-amidino-propane)hydrochloride-mediated and 3-morpholinosydnonimine-1-mediated low-density lipoprotein (LDL) oxidation in the thiobarbituric acid-reactive substances assay as well as the macrophage-mediated LDL oxidation. Compounds 1 and 2 exhibited the potent antioxidant activities in the conjugated diene production, relative electrophoretic mobility, and apoB-100 fragmentation on copper-mediated LDL oxidation. Compound 1 also suppressed nitric oxide production and inducible nitric oxide synthase expression in lipopolysaccharide-stimulated RAW264.7 cells.-
dc.publisherAmer Chem Soc-
dc.titleAntioxidant activities of abietane diterpenoids isolated from Torreya nucifera leaves-
dc.title.alternativeAntioxidant activities of abietane diterpenoids isolated from Torreya nucifera leaves-
dc.typeArticle-
dc.citation.titleJournal of Agricultural and Food Chemistry-
dc.citation.number15-
dc.citation.endPage5374-
dc.citation.startPage5369-
dc.citation.volume54-
dc.contributor.affiliatedAuthorWoo Song Lee-
dc.contributor.affiliatedAuthorJong Min Han-
dc.contributor.affiliatedAuthorTae Sook Jeong-
dc.contributor.alternativeName이우송-
dc.contributor.alternativeName김주령-
dc.contributor.alternativeName한종민-
dc.contributor.alternativeName장기창-
dc.contributor.alternativeName석대은-
dc.contributor.alternativeName정태숙-
dc.identifier.bibliographicCitationJournal of Agricultural and Food Chemistry, vol. 54, no. 15, pp. 5369-5374-
dc.identifier.doi10.1021/jf060896c-
dc.subject.keywordAbietane diterpenoids-
dc.subject.keywordAntioxidant activity-
dc.subject.keywordAtherosclerosis-
dc.subject.keywordINOS-
dc.subject.keywordLDL-
dc.subject.keywordNO-
dc.subject.keywordTorreya nucifera-
dc.subject.localAbietane diterpenoids-
dc.subject.localAbietane diterpenoid-
dc.subject.localAntioxidant activity-
dc.subject.localanti-oxidants activity-
dc.subject.localAnti-oxidant activity-
dc.subject.localantioxidant activity-
dc.subject.localanti-oxidant activity-
dc.subject.localatherosclerosis-
dc.subject.localAtherosclerosis-
dc.subject.localatheroclerosis-
dc.subject.localInducible nitric oxide synthase (iNOS)-
dc.subject.localInducible nitric oxide synthase-
dc.subject.localinducible nnitric oxide synthase-
dc.subject.localiNOS-
dc.subject.localInducible nitric oxide synthease (iNOS)-
dc.subject.localINOS-
dc.subject.localinducible nitric oxide synthase-
dc.subject.localLDL-
dc.subject.localNO-
dc.subject.localnitric oxide-
dc.subject.localnitric oxide (NO)-
dc.subject.localNitric oxide-
dc.subject.localNO (Nitric oxide)-
dc.subject.localnitric oxide.-
dc.subject.localNitric oxid-
dc.subject.localNitric oxide (NO)-
dc.subject.localTorreya nucifera-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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