Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors = PRL-3의 inhibitor인 rhodanine유도체들의 합성과 생물학적 평가

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dc.contributor.authorJ H Ahn-
dc.contributor.authorSeung Jun Kim-
dc.contributor.authorW S Park-
dc.contributor.authorS Y Cho-
dc.contributor.authorJ D Ha-
dc.contributor.authorS S Kim-
dc.contributor.authorS K Kang-
dc.contributor.authorDae Gwin Jeong-
dc.contributor.authorSuk-Kyeong Jung-
dc.contributor.authorSang-Hyeup Lee-
dc.contributor.authorHwan Mook Kim-
dc.contributor.authorSong Kyu Park-
dc.contributor.authorKiho Lee-
dc.contributor.authorChang Woo Lee-
dc.contributor.authorSeong Eon Ryu-
dc.contributor.authorJ K Choi-
dc.date.accessioned2017-04-19T09:04:53Z-
dc.date.available2017-04-19T09:04:53Z-
dc.date.issued2006-
dc.identifier.issn0960894X-
dc.identifier.uri10.1016/j.bmcl.2006.02.060ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7497-
dc.description.abstractA series of rhodanine derivatives was synthesized and evaluated for their ability to inhibit PRL-3. Benzylidene rhodanine derivative showed good biological activity, while compound 5e was the most active in this series exhibiting an IC50 value of 0.9 μM in vitro and showed a reduced invasion in cell-based assay.-
dc.publisherElsevier-
dc.titleSynthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors = PRL-3의 inhibitor인 rhodanine유도체들의 합성과 생물학적 평가-
dc.title.alternativeSynthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors-
dc.typeArticle-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.number11-
dc.citation.endPage2999-
dc.citation.startPage2996-
dc.citation.volume16-
dc.contributor.affiliatedAuthorSeung Jun Kim-
dc.contributor.affiliatedAuthorDae Gwin Jeong-
dc.contributor.affiliatedAuthorChang Woo Lee-
dc.contributor.alternativeName안진희-
dc.contributor.alternativeName김승준-
dc.contributor.alternativeName박월성-
dc.contributor.alternativeName조성윤-
dc.contributor.alternativeName하재두-
dc.contributor.alternativeName김성수-
dc.contributor.alternativeName강승규-
dc.contributor.alternativeName정대균-
dc.contributor.alternativeName정숙경-
dc.contributor.alternativeName이상협-
dc.contributor.alternativeName김환묵-
dc.contributor.alternativeName박성규-
dc.contributor.alternativeName이기호-
dc.contributor.alternativeName이창우-
dc.contributor.alternativeName류성언-
dc.contributor.alternativeName최중권-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, vol. 16, no. 11, pp. 2996-2999-
dc.identifier.doi10.1016/j.bmcl.2006.02.060-
dc.subject.keywordcancer-
dc.subject.keywordinhibitor-
dc.subject.keywordmetastasis-
dc.subject.keywordPRL-3-
dc.subject.keywordrhodanine-
dc.subject.localcancer-
dc.subject.localinhibitor-
dc.subject.localInhibitor-
dc.subject.localmetastasis-
dc.subject.localMetastasis-
dc.subject.localPRL-3-
dc.subject.localrhodanine-
dc.subject.localRhodanine-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
Ochang Branch Institute > Division of Bioinfrastructure > Laboratory Animal Resource Center > 1. Journal Articles
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