Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata = 꾸지뽕나무로부터 분리한 카테콜릭잔톤 및 플라보노이드 항동맥경화 및
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | K H Park | - |
| dc.contributor.author | Yong-Dae Park | - |
| dc.contributor.author | Jong Min Han | - |
| dc.contributor.author | K R Im | - |
| dc.contributor.author | B W Lee | - |
| dc.contributor.author | I Y Jeong | - |
| dc.contributor.author | Tae Sook Jeong | - |
| dc.contributor.author | Woo Song Lee | - |
| dc.date.accessioned | 2017-04-19T09:05:04Z | - |
| dc.date.available | 2017-04-19T09:05:04Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2006.08.032 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7566 | - |
| dc.description.abstract | The catecholic xanthones and flavonoids 1-13 were isolated from the root bark of Cudrania tricuspidata. Compounds 1 and 3-8 exhibited significant antioxidant activity against low-density lipoprotein (LDL) oxidation in the thiobarbituric acid-reactive substance (TBARS) assay. Among them, prenylated flavonoids 10-12 showed an inhibitory effect on the NO production and iNOS expression in RAW264.7 cells. Also, compounds 1, 2, 5, 7, 9, and 11 preferentially inhibited hACAT-2 than hACAT-1, whereas compounds 3, 4, 6, and 8 showed a similar specificity against hACAT-1 and -2. However, flavonoids 10, 12, and 13 dominantly inhibited hACAT-2, not hACAT-1. | - |
| dc.publisher | Elsevier | - |
| dc.title | Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata = 꾸지뽕나무로부터 분리한 카테콜릭잔톤 및 플라보노이드 항동맥경화 및 | - |
| dc.title.alternative | Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 21 | - |
| dc.citation.endPage | 5583 | - |
| dc.citation.startPage | 5580 | - |
| dc.citation.volume | 16 | - |
| dc.contributor.affiliatedAuthor | Yong-Dae Park | - |
| dc.contributor.affiliatedAuthor | Jong Min Han | - |
| dc.contributor.affiliatedAuthor | Tae Sook Jeong | - |
| dc.contributor.affiliatedAuthor | Woo Song Lee | - |
| dc.contributor.alternativeName | 박기훈 | - |
| dc.contributor.alternativeName | 박용대 | - |
| dc.contributor.alternativeName | 한종민 | - |
| dc.contributor.alternativeName | 임경란 | - |
| dc.contributor.alternativeName | 이병원 | - |
| dc.contributor.alternativeName | 정일윤 | - |
| dc.contributor.alternativeName | 정태숙 | - |
| dc.contributor.alternativeName | 이우송 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 21, pp. 5580-5583 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2006.08.032 | - |
| dc.subject.keyword | ACAT inhibitor | - |
| dc.subject.keyword | LDL-antioxidant | - |
| dc.subject.keyword | Nitric oxide | - |
| dc.subject.keyword | RAW264.7 cells | - |
| dc.subject.local | ACAT inhibitor | - |
| dc.subject.local | ACAT inhibitors | - |
| dc.subject.local | LDL-antioxidant | - |
| dc.subject.local | NO | - |
| dc.subject.local | NO (Nitric oxide) | - |
| dc.subject.local | Nitric oxid | - |
| dc.subject.local | Nitric oxide | - |
| dc.subject.local | Nitric oxide (NO) | - |
| dc.subject.local | nitric oxide | - |
| dc.subject.local | nitric oxide (NO) | - |
| dc.subject.local | nitric oxide. | - |
| dc.subject.local | RAW264.7 cells | - |
| dc.subject.local | Raw264.7 cells | - |
| dc.description.journalClass | Y | - |
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- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
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