Phenolic glycosides with antioxidant activity from the stem bark of Populus davidiana

Abstract

Phytochemical study on the EtOAc-soluble fraction of the stem bark of Populus davidiana resulted in the isolation of 10 phenolic glycosides (1-10), which were identified on the basis of physicochemical and spectroscopic analyses. Among these, three new compounds, populosides A-C (1-3), were determined to be 2-coumaroylmethyl-4-hydroxyphenyl-β-D-glucopyranoside, 2-coumaroylmethylphenyl-β-D-glucopyranoside, and 2-feruoylmethylphenyl- β-D-glucopyranoside, respectively. Compounds 1-10 were tested for their radical scavenging activity against an azo radical, ABTS.+. of these, populosides A-C (1-3), populoside (4), grandidentatin (8), salireposide (9), and coumaroyl-β-D-glucoside (10) exhibited antioxidant activity in this assay.