The effect of erythrodiol-3-acetate on the expressions of matrix metalloproteinase-1 and type-1 procollagen caused by ultraviolet irradiated cultured primary old aged human skin fibroblasts
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | H I Moon | - |
| dc.contributor.author | Joongku Lee | - |
| dc.contributor.author | J H Chung | - |
| dc.date.accessioned | 2017-04-19T09:05:30Z | - |
| dc.date.available | 2017-04-19T09:05:30Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.issn | 0944-7113 | - |
| dc.identifier.uri | 10.1016/j.phymed.2005.10.001 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7656 | - |
| dc.description.abstract | Methanol and aqueous extracts of Styrax japonica used traditionally for the treatments of skin elastic materials were screened in vitro for the matrix metalloproteinase (MMP)-1 inhibitor actions. The methylene chloride soluble fraction of methanol extract from the stems of S. japonica showed significant MMP-1 inhibition in primary old aged human skin fibroblasts caused by ultraviolet (UV) irradiation. Main triterpenoids were isolated by repeated column chromatography. Among them, the triterpenoid erythrodiol-3-acetate reduced the expression of MMP-1 and induced the expression of type-1 procollagen at the protein levels in a dose-dependent manner caused by UV irradiated cultured old aged human skin fibroblasts. Taken together, our results suggest that erythrodiol-3-acetate plays an important role in the skin aging process caused by UV irradiation. | - |
| dc.publisher | Elsevier | - |
| dc.title | The effect of erythrodiol-3-acetate on the expressions of matrix metalloproteinase-1 and type-1 procollagen caused by ultraviolet irradiated cultured primary old aged human skin fibroblasts | - |
| dc.title.alternative | The effect of erythrodiol-3-acetate on the expressions of matrix metalloproteinase-1 and type-1 procollagen caused by ultraviolet irradiated cultured primary old aged human skin fibroblasts | - |
| dc.type | Article | - |
| dc.citation.title | Phytomedicine | - |
| dc.citation.number | 9 | - |
| dc.citation.endPage | 711 | - |
| dc.citation.startPage | 707 | - |
| dc.citation.volume | 13 | - |
| dc.contributor.affiliatedAuthor | Joongku Lee | - |
| dc.contributor.alternativeName | 문형인 | - |
| dc.contributor.alternativeName | 이중구 | - |
| dc.contributor.alternativeName | 정진호 | - |
| dc.identifier.bibliographicCitation | Phytomedicine, vol. 13, no. 9, pp. 707-711 | - |
| dc.identifier.doi | 10.1016/j.phymed.2005.10.001 | - |
| dc.subject.keyword | erythrodiol-3-acetate | - |
| dc.subject.keyword | matrix metalloproteinase-1 | - |
| dc.subject.keyword | type-1 procollagen | - |
| dc.subject.keyword | ultra violet | - |
| dc.subject.local | erythrodiol-3-acetate | - |
| dc.subject.local | Matrix metalloproteinase MMP-1 | - |
| dc.subject.local | Matrix metalloproteinase-1 | - |
| dc.subject.local | matrix metalloproteinase (MMP)-1 | - |
| dc.subject.local | matrix metalloproteinase-1 | - |
| dc.subject.local | matrix metalloproteinase-1 inhibitor | - |
| dc.subject.local | type-1 procollagen | - |
| dc.subject.local | ultra violet | - |
| dc.description.journalClass | Y | - |
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