Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Talosins A and B: new isoflavonol glycosides with potent antifungal activity from Kitasatospora kifunensis MJM341: 2. physicochemical properties and structure determination
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- Title
- Talosins A and B: new isoflavonol glycosides with potent antifungal activity from Kitasatospora kifunensis MJM341: 2. physicochemical properties and structure determination
- Author(s)
- Won Gon Kim; T M Yoon; H J Kwon; J W Suh
- Bibliographic Citation
- Journal of Antibiotics, vol. 59, no. 10, pp. 640-645
- Publication Year
- 2006
- Abstract
- In our screening program for new antifungal agents from microbial secondary metabolites, two new isoflavonol glycosides with potent antifungal activity, talosins A and B, were isolated from the culture broth of Kitasatospora kifunensis MJM341. Talosins A and B were determined to be genistein 7-α-L-6-deoxy-talopyranoside and genistein 4′,7-di-α-L-6- deoxy-talopyranoside, respectively, by spectroscopic studies. They are the first flavonoid glycosides incorporating 6-deoxy-talose as a sugar component.
- Keyword
- kitasatospora kifunensistalosin Atalosin Bisoflavonol glycoside6-deoxy-taloseantifungal agentgenistein
- ISSN
- 0021-8820
- Publisher
- Springer-Nature Pub Group
- Full Text Link
- http://dx.doi.org/10.1038/ja.2006.85
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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