Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

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Title
Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation
Author(s)
E Oh; D Lee; Y P Kim; Seung Youp Cha; Doo-Byoung Oh; Hyun Ah Kang; J Kim; H S Kim
Bibliographic Citation
Angewandte Chemie-International Edition, vol. 45, no. 47, pp. 7959-7963
Publication Year
2006
Abstract
(Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence.
Keyword
CarbohydratesEnergy transferGlycoproteinsGold nanoparticlesQuantum dots
ISSN
1433-7851
Publisher
Wiley
DOI
http://dx.doi.org/10.1002/anie.200601948
Type
Article
Appears in Collections:
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
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