Analysis of a prodigiosin biosynthetic gene cluster from the marine bacterium Hahella chejuensis KCTC 2396 = 해양세균 하헬라 제주엔시스의 프로디지오신 생합성 유전자 군 분석

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dc.contributor.authorD Kim-
dc.contributor.authorYon Kyoung Park-
dc.contributor.authorJong Suk Lee-
dc.contributor.authorJihyun Kim-
dc.contributor.authorHaeyoung Jeong-
dc.contributor.authorB S Kim-
dc.contributor.authorC H Lee-
dc.date.accessioned2017-04-19T09:05:39Z-
dc.date.available2017-04-19T09:05:39Z-
dc.date.issued2006-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/7704-
dc.description.abstractMarine bacterium Hahella chejuensis KCTC 2396 simultaneously produced red antibiotic prodigiosin and undecylprodiginine. A complete set of the prodigiosin biosynthetic gene cluster has been cloned, sequenced, and successfully expressed in a heterologous host. Sequence analysis of the gene cluster revealed 14 ORFs showing high similarity to pig and red genes from Serratia spp. and Streptomyces coelicolor A3(2), respectively, and the gene organization was almost similar to that of pig genes. These genes were named hap for Hahella prodigiosin, and determined to be transcribed as a single operon, by RT-PCR experiment. Based on the hap gene mutagenesis experiments and comparative analysis with pig and red genes, we propose a prodigiosin-biosynthetic pathway in KCTC 2396.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleAnalysis of a prodigiosin biosynthetic gene cluster from the marine bacterium Hahella chejuensis KCTC 2396 = 해양세균 하헬라 제주엔시스의 프로디지오신 생합성 유전자 군 분석-
dc.title.alternativeAnalysis of a prodigiosin biosynthetic gene cluster from the marine bacterium Hahella chejuensis KCTC 2396-
dc.typeArticle-
dc.citation.titleJournal of Microbiology and Biotechnology-
dc.citation.number12-
dc.citation.endPage1918-
dc.citation.startPage1912-
dc.citation.volume16-
dc.contributor.affiliatedAuthorYon Kyoung Park-
dc.contributor.affiliatedAuthorJong Suk Lee-
dc.contributor.affiliatedAuthorJihyun Kim-
dc.contributor.affiliatedAuthorHaeyoung Jeong-
dc.contributor.alternativeName김덕규-
dc.contributor.alternativeName박연경-
dc.contributor.alternativeName이종석-
dc.contributor.alternativeName김지현-
dc.contributor.alternativeName정해영-
dc.contributor.alternativeName김범석-
dc.contributor.alternativeName이충환-
dc.identifier.bibliographicCitationJournal of Microbiology and Biotechnology, vol. 16, no. 12, pp. 1912-1918-
dc.subject.keywordalgicidal agent-
dc.subject.keywordhap-
dc.subject.keywordmarine bacterium-
dc.subject.keywordprodigiosin-
dc.subject.localalgicidal agent-
dc.subject.localAlgicidal agent-
dc.subject.localhap-
dc.subject.localMarine bacterium-
dc.subject.localmarine bacterium-
dc.subject.localmarine bacteria-
dc.subject.localMarine bacteria-
dc.subject.localProdigiosin-
dc.subject.localprodigiosin-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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