A new sesquiterpene ester inhibiting no production from the fruits of Celastrus orbiculatus

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Title
A new sesquiterpene ester inhibiting no production from the fruits of Celastrus orbiculatus
Author(s)
Jung Joon Lee
Bibliographic Citation
Journal of Asian Natural Products Research, vol. 8, no. 8, pp. 739-742
Publication Year
2006
Abstract
A new β-dihydroagarofuran sesquiterpene ester, 1β,2β, 6α, 13-tetraacetoxy-9α-cinnamoyloxy-β-dihydroagarofuran (1), and the known compound 1β,6α,13-triacetoxy-9α-benzoyloxy- β-dihydroagarofuran (2), have been isolated from the fruits of Celastrus orbiculatus Thunb. Their structures have been elucidated on the basis of spectroscopic methods. Compound 1 shows moderate activity of inhibiting LPS-induced nitric oxide production in murine macrophage RAW264.7 cells, with an IC50 of 55.4 μM.
Keyword
1β,2β,6α,13-Tetraacetoxy-9α-cinnamoyloxy-β- dihydroagarofurancelastrus orbiculatussesquiterpene ester
ISSN
1028-6020
Publisher
T&F (Taylor & Francis)
DOI
http://dx.doi.org/10.1080/10286020412331286498
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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