Free radical-scavenging delta-lactones from Boletus calopus

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Title
Free radical-scavenging delta-lactones from Boletus calopus
Author(s)
Jin-Woo Kim; Ick Dong Yoo; Won Gon Kim
Bibliographic Citation
Planta Medica, vol. 72, no. 15, pp. 1431-1432
Publication Year
2006
Abstract
The methanol extracts from the fruiting body of the mushroom Boletus calopus showed free radical-scavenging activity. Bioactivity-guided fractionation of the methanol extracts led to a new hydroxylated calopin named calopin B, along with the known δ-lactones calopin and cyclocalopin A. The structure of the new calopin analogue was elucidated by spectroscopic methods. All compounds showed potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC50 values of 1.2-5.4 μg/mL.
ISSN
0032-0943
Publisher
Georg Thieme Verlag Kg
DOI
http://dx.doi.org/10.1055/s-2006-951722
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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