Triterpenoid saponin from Viola hondoensis W. Becker et H Boss. and their effect on MMP-1 and type I procollagen expression
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- Title
- Triterpenoid saponin from Viola hondoensis W. Becker et H Boss. and their effect on MMP-1 and type I procollagen expression
- Author(s)
- H I Moon; J H Chung; Joongku Lee; O P Zee
- Bibliographic Citation
- Archives of Pharmacal Research, vol. 27, no. 7, pp. 730-733
- Publication Year
- 2004
- Abstract
- Bioassay-guided fractionation has led to the isolation of triterpenoid saponins such as Acutoside A (3-O-[O-β-D-glucopyranosyl-(1→2)-O- β-D-glucopyranosyl] oleanolic acid) from the whole plants of Viola hondoensis. Among them, Saponin 1 exhibited potent inhibitory activity against matrix metalloproteinase (MMP)-1, and prevented the UV-induced changes in the MMP-1 expression. In addition, compound was isolated from this plant for the first time.
- ISSN
- 0253-6269
- Publisher
- Pharmaceutical Soc Korea
- Full Text Link
- http://dx.doi.org/10.1007/BF02980140
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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