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- Title
- Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi
- Author(s)
- N Kim; J C Shin; Won Cheol Kim; B Y Hwang; B S Kim; Young-Soo Hong; D Lee
- Bibliographic Citation
- Journal of Antibiotics, vol. 59, no. 12, pp. 797-800
- Publication Year
- 2006
- Abstract
- Two new 6-alkylsalicylic acids, salaceyins A and B were isolated by bioassay-guided fractionation from the culture of the endophytic Streptomyces laceyi MS53 and their structures were determined on the basis of spectroscopic data. Salaceyins A and B exhibited modest cytotoxicity against a human breast cancer cell line (SKBR3) with IC50 values of 3.0 and 5.5 μg/ml, respectively.
- Keyword
- Alkysalicylic acidCytotoxicStreptomyces
- ISSN
- 0021-8820
- Publisher
- Springer-Nature Pub Group
- DOI
- http://dx.doi.org/10.1038/ja.2006.105
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
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