(Aryloxyacetylamino)benzoic acid analogues: a new class of hypoxia-inducible factor-1 inhibitors
Cited 138 time in 
Metadata Downloads
- Title
- (Aryloxyacetylamino)benzoic acid analogues: a new class of hypoxia-inducible factor-1 inhibitors
- Author(s)
- Kyeong Lee; J H Lee; S K Boovanahalli; Y Jin; M Lee; X Jin; Jin Hwan Kim; Young-Soo Hong; Jung Joon Lee
- Bibliographic Citation
- Journal of Medicinal Chemistry, vol. 50, no. 7, pp. 1675-1684
- Publication Year
- 2007
- Abstract
- Structural modification of a compound discovered during screening using an HRE-dependent reporter assay has revealed a novel class of HIF-1 inhibitors, which potently inhibit the HIF-1α protein accumulation and its target gene expression under hypoxic conditions in human hepatocellular carcinoma Hep3B cells.
- ISSN
- 0022-2623
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/jm0610292
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.