Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | M K Moon | - |
| dc.contributor.author | H M Oh | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | N I Baek | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | J S Kim | - |
| dc.contributor.author | D K Kim | - |
| dc.date.accessioned | 2017-04-19T09:06:55Z | - |
| dc.date.available | 2017-04-19T09:06:55Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | 10.1007/BF02977609 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7871 | - |
| dc.description.abstract | The methanolic extract of the leaves of Liriodendron tulipifera was found to show inhibitory activity towards farnesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of lipiferolide, an inhibitor of FPTase. This compound inhibited the FPTase activity in a dose-dependent manner, and showed cell growth inhibitory activity against several tumor cells. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera | - |
| dc.title.alternative | Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 3 | - |
| dc.citation.endPage | 302 | - |
| dc.citation.startPage | 299 | - |
| dc.citation.volume | 30 | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.alternativeName | 문미경 | - |
| dc.contributor.alternativeName | 오현미 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.contributor.alternativeName | 김성훈 | - |
| dc.contributor.alternativeName | 김주신 | - |
| dc.contributor.alternativeName | 김대근 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 30, no. 3, pp. 299-302 | - |
| dc.identifier.doi | 10.1007/BF02977609 | - |
| dc.subject.keyword | cell growth inhibitory activity | - |
| dc.subject.keyword | FPTase | - |
| dc.subject.keyword | lipiferolide | - |
| dc.subject.keyword | liriodendron tulipifera | - |
| dc.subject.local | cell growth inhibitory activity | - |
| dc.subject.local | FPTase | - |
| dc.subject.local | lipiferolide | - |
| dc.subject.local | liriodendron tulipifera | - |
| dc.description.journalClass | Y | - |
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