Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Differential antiviral activity of benzastatin C and its dechlorinated derivative from Streptomyces nitrosporeus
Cited 21 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J G Lee | - |
| dc.contributor.author | Ick Dong Yoo | - |
| dc.contributor.author | Won Gon Kim | - |
| dc.date.accessioned | 2017-04-19T09:07:02Z | - |
| dc.date.available | 2017-04-19T09:07:02Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.issn | 0918-6158 | - |
| dc.identifier.uri | 10.1248/bpb.30.795 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/7890 | - |
| dc.description.abstract | Benzastatin C, a 3-chloro-tetrahydroquinolone alkaloid from Streptomyces nitrosporeus, showed antiviral activity in a dose-dependant manner with EC 50 values of 1.92, 0.53, and 1.99 μg/ml against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and vesicular stomatitis virus (VSV), respectively. In contrast, benzastatin D, the corresponding dechlorinated derivative, did not exhibit any antiviral activity. These results indicate that the antiviral activity of benzastatin C is mediated, in part, due to the chlorine moiety in its molecular structure. | - |
| dc.publisher | Pharmaceutical Soc Japan | - |
| dc.title | Differential antiviral activity of benzastatin C and its dechlorinated derivative from Streptomyces nitrosporeus | - |
| dc.title.alternative | Differential antiviral activity of benzastatin C and its dechlorinated derivative from Streptomyces nitrosporeus | - |
| dc.type | Article | - |
| dc.citation.title | Biological & Pharmaceutical Bulletin | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 797 | - |
| dc.citation.startPage | 795 | - |
| dc.citation.volume | 30 | - |
| dc.contributor.affiliatedAuthor | Ick Dong Yoo | - |
| dc.contributor.affiliatedAuthor | Won Gon Kim | - |
| dc.contributor.alternativeName | 이종교 | - |
| dc.contributor.alternativeName | 유익동 | - |
| dc.contributor.alternativeName | 김원곤 | - |
| dc.identifier.bibliographicCitation | Biological & Pharmaceutical Bulletin, vol. 30, no. 4, pp. 795-797 | - |
| dc.identifier.doi | 10.1248/bpb.30.795 | - |
| dc.subject.keyword | Antiviral activity | - |
| dc.subject.keyword | Benzastatin C | - |
| dc.subject.keyword | Chloro-tetrahydroquinolone | - |
| dc.subject.keyword | Streptomyces nitrosporeus | - |
| dc.subject.local | Antiviral activity | - |
| dc.subject.local | antiviral activity | - |
| dc.subject.local | Benzastatin C | - |
| dc.subject.local | Chloro-tetrahydroquinolone | - |
| dc.subject.local | Streptomyces nitrosporeus | - |
| dc.subject.local | streptomyces nitrosporeus | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.