Isolation of constituents and anti-complement activity from Acer okamotoanum
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- Title
- Isolation of constituents and anti-complement activity from Acer okamotoanum
- Author(s)
- W Y Jin; B S Min; J P Lee; P T Thuong; Hyeong Kyu Lee; K S Song; Y H Seong; K H Bae
- Bibliographic Citation
- Archives of Pharmacal Research, vol. 30, no. 2, pp. 172-176
- Publication Year
- 2007
- Abstract
- A novel acylated sterol glucoside (1) along with four known compounds, β-amyrin acetate (2), 3β,24-dihydroxytaraxer-14-ene (3), cleomiscosin A (4), and cleomiscosin C (5), were isolated from the leaf and twig of Acer okamotoanum Nakai (Aceraceae). The structure of the new compound was determined to be β-sitosterol glucoside-3′-O-hexacosanoicate based on chemical and spectroscopic analyses. In addition, the novel compound was found to exhibit a significant inhibitory effect (IC50 value of 0.2 μM) on the complement system activated by the classical pathway.
- Keyword
- Acer okamotoanum; Aceraceae; Acylated sterol glucoside; Anti-complement activity; β-Sitosterol glucoside-3′-O-hexacosanoicate
- ISSN
- 0253-6269
- Publisher
- Pharmaceutical Soc Korea
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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