Polyketides from a sponge-derived fungus, Aspergillus versicolor
Cited 0 time in
- Polyketides from a sponge-derived fungus, Aspergillus versicolor
- Y M Lee; T A Mansoor; J Hong; C O Lee; Kyung Sook Bae; J H Jung
- Bibliographic Citation
- Natural Products Sciences, vol. 13, no. 1, pp. 90-96
- Publication Year
- Bioactivity guided fractionation of the cultured filtrates of Aspergillus versicolor, which was derived from a marine sponge Petrosia sp., yielded three polyketides: decumbenones A (1), B (2), and versiol (3). These compounds were identified on the basis of 1D and 2D NMR spectroscopic and MS analysis. The absolute configuration was defined by the modified Mosher's method. The isolated compounds were tested for cytotoxicity against a panel of five human solid tumor cell lines and antibacterial activity against twenty clinically isolated methicillin-resistant strains. This is the first report on the isolation of these compounds from a marine source.
- aspergillus versicolor; decumbenones A and B; petrosia sp.; polyketide; sponge-derived fungi; versiol
- Korean Society of Pharmacognosy
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.