Isoprenylated flavonoids from the stem bark of Erythrina abyssinica
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- Title
- Isoprenylated flavonoids from the stem bark of Erythrina abyssinica
- Author(s)
- L Cui; D T Ndinteh; M K Na; P T Thuong; J S Muruumu; D Njamen; J T Mbafor; Z T Fomum; Jong Seog Ahn; Won Keun Oh
- Bibliographic Citation
- Journal of Natural Products, vol. 70, no. 6, pp. 1039-1042
- Publication Year
- 2007
- Abstract
- Three new prenylated flavanones, abyssinoflavanones V, VI, and VII (1-3), together with eight known flavanones (4-11) and two chalcones (12-13), were isolated from the stem bark of Erythrina abyssinica. Their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All the isolates, with the exception of 1 and 8, strongly inhibited PTP1B activity in an in vitro assay with IC50 values ranging from 14.2 ± 1.7 to 26.7 ± 1.2 μM.
- ISSN
- 0163-3864
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/np060477+
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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