New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction

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Title
New triterpene glucosides, oligoporins A-C, from Oligoporus tephroleucus protect DNA from Fenton reaction
Author(s)
In Kyoung Lee; Yun Woo Jang; S H Yu; Bong Sik Yun
Bibliographic Citation
Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 17, pp. 4906-4909
Publication Year
2007
Abstract
New triterpene glucosides, oligoporins A (1), B (2), and C (3), were isolated from the methanolic extract of the fruiting bodies of Oligoporus tephroleucus (Polyporaceae). Their structures were established by spectroscopic methods. These compounds significantly exhibited protective effect to plasmid DNA damage by hydroxyl radical (·OH) generated from the Fenton reaction with hydrogen peroxide and ferrous.
Keyword
DNA protectionFenton reactionOligoporinsOligoporus tephroleucus
ISSN
0960-894X
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/j.bmcl.2007.06.034
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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