Synthesis and structure-activity relationship of novel indene N-oxide derivatives as potent peroxisome proliferator activated receptor γ (PPARγ) agonists
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J H Ahn | - |
| dc.contributor.author | M S Shin | - |
| dc.contributor.author | S H Jung | - |
| dc.contributor.author | J A Kim | - |
| dc.contributor.author | H M Kim | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | S K Kang | - |
| dc.contributor.author | K R Kim | - |
| dc.contributor.author | S D Rhee | - |
| dc.contributor.author | S D Park | - |
| dc.contributor.author | J M Lee | - |
| dc.contributor.author | Jeong-Hyung Lee | - |
| dc.contributor.author | H G Cheon | - |
| dc.contributor.author | S S Kim | - |
| dc.date.accessioned | 2017-04-19T09:07:47Z | - |
| dc.date.available | 2017-04-19T09:07:47Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2007.06.073 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8019 | - |
| dc.description.abstract | A series of novel indene N-oxide derivatives were prepared by various synthetic methods and evaluated for their ability to activate PPARγ. The best PPARγ agonist in this series was 9 h, which showed an EC50 value of 15 nM. | - |
| dc.publisher | Elsevier | - |
| dc.title | Synthesis and structure-activity relationship of novel indene N-oxide derivatives as potent peroxisome proliferator activated receptor γ (PPARγ) agonists | - |
| dc.title.alternative | Synthesis and structure-activity relationship of novel indene N-oxide derivatives as potent peroxisome proliferator activated receptor γ (PPARγ) agonists | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 18 | - |
| dc.citation.endPage | 5244 | - |
| dc.citation.startPage | 5239 | - |
| dc.citation.volume | 17 | - |
| dc.contributor.affiliatedAuthor | Jeong-Hyung Lee | - |
| dc.contributor.alternativeName | 안진희 | - |
| dc.contributor.alternativeName | 신미식 | - |
| dc.contributor.alternativeName | 정선호 | - |
| dc.contributor.alternativeName | 김진아 | - |
| dc.contributor.alternativeName | 김혜민 | - |
| dc.contributor.alternativeName | 김세환 | - |
| dc.contributor.alternativeName | 강승규 | - |
| dc.contributor.alternativeName | 김광록 | - |
| dc.contributor.alternativeName | 이상달 | - |
| dc.contributor.alternativeName | 박성대 | - |
| dc.contributor.alternativeName | 이재목 | - |
| dc.contributor.alternativeName | 이정형 | - |
| dc.contributor.alternativeName | 천혜경 | - |
| dc.contributor.alternativeName | 김성수 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 18, pp. 5239-5244 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2007.06.073 | - |
| dc.subject.keyword | diabetes | - |
| dc.subject.keyword | indene N-oxide | - |
| dc.subject.keyword | PPARγ | - |
| dc.subject.local | Diabetes | - |
| dc.subject.local | diabetes | - |
| dc.subject.local | indene N-oxide | - |
| dc.subject.local | PPAR-γ | - |
| dc.subject.local | PPARγ | - |
| dc.subject.local | PPAR-gamma | - |
| dc.description.journalClass | Y | - |
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