DC Field | Value | Language |
---|---|---|
dc.contributor.author | H J Shin | - |
dc.contributor.author | H S Jeong | - |
dc.contributor.author | H S Lee | - |
dc.contributor.author | Song Kyu Park | - |
dc.contributor.author | Hwan Mook Kim | - |
dc.contributor.author | H J Kwon | - |
dc.date.accessioned | 2017-04-19T09:07:48Z | - |
dc.date.available | 2017-04-19T09:07:48Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8028 | - |
dc.description.abstract | An antiproliferative agent, streptochlorin, was isolated from the fermentation broth of a marine actinomycete isolated from marine sediment. Phylogenetic analysis of the 16S rRNA gene sequence indicated that the strain belongs to the genus Streptomyces. Bioactivity guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and reversed-phase HPLC gave a pure compound, streptochlorin. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Streptochlorin exhibited significant antiproliferative activity against human cultured cell lines. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110 | - |
dc.title.alternative | Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110 | - |
dc.type | Article | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.number | 8 | - |
dc.citation.endPage | 1406 | - |
dc.citation.startPage | 1403 | - |
dc.citation.volume | 17 | - |
dc.contributor.affiliatedAuthor | Song Kyu Park | - |
dc.contributor.affiliatedAuthor | Hwan Mook Kim | - |
dc.contributor.alternativeName | 신희재 | - |
dc.contributor.alternativeName | 정현선 | - |
dc.contributor.alternativeName | 이희승 | - |
dc.contributor.alternativeName | 박성규 | - |
dc.contributor.alternativeName | 김환묵 | - |
dc.contributor.alternativeName | 권호정 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, vol. 17, no. 8, pp. 1403-1406 | - |
dc.subject.keyword | antiproliferative agent | - |
dc.subject.keyword | streptochlorin | - |
dc.subject.keyword | streptomyces sp. 04DH110 | - |
dc.subject.local | antiproliferative agent | - |
dc.subject.local | streptochlorin | - |
dc.subject.local | streptomyces sp. 04DH110 | - |
dc.description.journalClass | Y | - |
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