Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110

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dc.contributor.authorH J Shin-
dc.contributor.authorH S Jeong-
dc.contributor.authorH S Lee-
dc.contributor.authorSong Kyu Park-
dc.contributor.authorHwan Mook Kim-
dc.contributor.authorH J Kwon-
dc.date.accessioned2017-04-19T09:07:48Z-
dc.date.available2017-04-19T09:07:48Z-
dc.date.issued2007-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8028-
dc.description.abstractAn antiproliferative agent, streptochlorin, was isolated from the fermentation broth of a marine actinomycete isolated from marine sediment. Phylogenetic analysis of the 16S rRNA gene sequence indicated that the strain belongs to the genus Streptomyces. Bioactivity guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and reversed-phase HPLC gave a pure compound, streptochlorin. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Streptochlorin exhibited significant antiproliferative activity against human cultured cell lines.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleIsolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110-
dc.title.alternativeIsolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110-
dc.typeArticle-
dc.citation.titleJournal of Microbiology and Biotechnology-
dc.citation.number8-
dc.citation.endPage1406-
dc.citation.startPage1403-
dc.citation.volume17-
dc.contributor.affiliatedAuthorSong Kyu Park-
dc.contributor.affiliatedAuthorHwan Mook Kim-
dc.contributor.alternativeName신희재-
dc.contributor.alternativeName정현선-
dc.contributor.alternativeName이희승-
dc.contributor.alternativeName박성규-
dc.contributor.alternativeName김환묵-
dc.contributor.alternativeName권호정-
dc.identifier.bibliographicCitationJournal of Microbiology and Biotechnology, vol. 17, no. 8, pp. 1403-1406-
dc.subject.keywordantiproliferative agent-
dc.subject.keywordstreptochlorin-
dc.subject.keywordstreptomyces sp. 04DH110-
dc.subject.localantiproliferative agent-
dc.subject.localstreptochlorin-
dc.subject.localstreptomyces sp. 04DH110-
dc.description.journalClassY-
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