Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

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Title
Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha
Author(s)
Yun Woo Jang; In Kyoung Lee; Young Sook Kim; Sangku Lee; Ho Jae Lee; S H Yu; Bong Sik Yun
Bibliographic Citation
Journal of Antibiotics, vol. 60, no. 11, pp. 696-699
Publication Year
2007
Abstract
Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.
Keyword
antifungal activitymushroompolypropionatexylaria polymorphaxylarinic acid
ISSN
0021-8820
Publisher
Springer-Nature Pub Group
DOI
http://dx.doi.org/10.1038/ja.2007.89
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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