DC Field | Value | Language |
---|---|---|
dc.contributor.author | C Z Wu | - |
dc.contributor.author | X F Cai | - |
dc.contributor.author | N T Dat | - |
dc.contributor.author | S S Hong | - |
dc.contributor.author | A R Han | - |
dc.contributor.author | E K Seo | - |
dc.contributor.author | B Y Hwang | - |
dc.contributor.author | J X Nan | - |
dc.contributor.author | D Lee | - |
dc.contributor.author | Jung Joon Lee | - |
dc.date.accessioned | 2017-04-19T09:08:30Z | - |
dc.date.available | 2017-04-19T09:08:30Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0040-4039 | - |
dc.identifier.uri | 10.1016/j.tetlet.2007.10.059 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8176 | - |
dc.description.abstract | Two novel dimeric meroterpenoids, bisbakuchiols A and B, along with (S)-bakuchiol were isolated from the seeds of Psoralea corylifolia L. (Fabaceae). Bisbakuchiols A and B contain an unprecedented dimeric meroterpenoid skeleton in which two meroterpenes are linked through a dioxane bridge. All compounds were evaluated for their potential to inhibit hypoxia-inducible factor-1 (HIF-1) activation induced by hypoxia in a HIF-1-mediated reporter gene assay in AGS human gastric cancer cells. (S)-Bakuchiol inhibited hypoxic activation of HIF-1 with an IC50 value of 6.1 μM. | - |
dc.publisher | Elsevier | - |
dc.title | Bisbakuchiols A and B, novel dimeric meroterpenoids from Psoralea corylifolia | - |
dc.title.alternative | Bisbakuchiols A and B, novel dimeric meroterpenoids from Psoralea corylifolia | - |
dc.type | Article | - |
dc.citation.title | Tetrahedron Letters | - |
dc.citation.number | 50 | - |
dc.citation.endPage | 8864 | - |
dc.citation.startPage | 8861 | - |
dc.citation.volume | 48 | - |
dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
dc.contributor.alternativeName | Wu | - |
dc.contributor.alternativeName | Cai | - |
dc.contributor.alternativeName | Dat | - |
dc.contributor.alternativeName | 홍성수 | - |
dc.contributor.alternativeName | 한아름 | - |
dc.contributor.alternativeName | 서은경 | - |
dc.contributor.alternativeName | 황방연 | - |
dc.contributor.alternativeName | Nan | - |
dc.contributor.alternativeName | 이동호 | - |
dc.contributor.alternativeName | 이정준 | - |
dc.identifier.bibliographicCitation | Tetrahedron Letters, vol. 48, no. 50, pp. 8861-8864 | - |
dc.identifier.doi | 10.1016/j.tetlet.2007.10.059 | - |
dc.subject.keyword | Fabaceae | - |
dc.subject.keyword | Hypoxia-inducible factor-1 | - |
dc.subject.keyword | Meroterpenoid | - |
dc.subject.keyword | Psoralea corylifolia | - |
dc.subject.local | fabaceae | - |
dc.subject.local | Fabaceae | - |
dc.subject.local | hypoxia-inducible factor-1 (HIF-1) | - |
dc.subject.local | Hypoxiainducible factor 1 | - |
dc.subject.local | Hypoxia-inducible factor-1 | - |
dc.subject.local | Meroterpenoid | - |
dc.subject.local | Meroterpenoids | - |
dc.subject.local | Psoralea corylifolia L. | - |
dc.subject.local | Psoralea corylifolia | - |
dc.description.journalClass | Y | - |
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