Harzianums A and B produced by a fungal strain, Hypocrea sp. F000527, and their cytotoxicity against tumor cell lines

Cited 13 time in scopus
Metadata Downloads
Title
Harzianums A and B produced by a fungal strain, Hypocrea sp. F000527, and their cytotoxicity against tumor cell lines
Author(s)
H Z Jin; J H Lee; W D Zhang; H B Lee; Young-Soo Hong; Y H Kim; Jung Joon Lee
Bibliographic Citation
Journal of Asian Natural Products Research, vol. 9, no. 3, pp. 203-207
Publication Year
2007
Abstract
A new compound, harzianum B (1), was isolated from the culture broth of a fungal strain, Hypocrea sp. F000527, together with a known trichothecene, harzianum A (2). Its structure was determined by spectroscopic analyses including HRFAB-MS and various 1H NMR and 13C NMR spectral data. Harzianum B (1) was characterised as (E,Z,E)-2′, 4′, 6′-octatriendioic acid esterified on the 4β-hydroxyl group of trichodermol. Harzianums A (2) and B (1) showed cytotoxicity against several human cancer cell lines.
Keyword
CytotoxicityHarzianum BHypocrea spTumor cell lines
ISSN
1028-6020
Publisher
T&F (Taylor & Francis)
DOI
http://dx.doi.org/10.1080/10286020500531977
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.