Plasmonic magnetic nanostructure for bimodal imaging and photonic-based therapy of cancer cells

Cited 35 time in scopus
Metadata Downloads
Title
Plasmonic magnetic nanostructure for bimodal imaging and photonic-based therapy of cancer cells
Author(s)
Yong Taik Lim; Mi Young Cho; Jin Kyeong Kim; S Hwangbo; Bong Hyun Chung
Bibliographic Citation
Chembiochem, vol. 8, no. 18, pp. 2204-2209
Publication Year
2007
Abstract
In summary, we synthesized a novel nanostructure that has NIR-absorbing (and scattering) optical characteristics and magnetic-responsive moieties for MRI. The nanocomposite particles were successfully demonstrated for use as bimodal-imaging contrast agents as well as photonic-based therapeutic agents for cancer cells. As a perspective of this research, we expect that these nanocomposite particles would enable biologists or medical doctors to gather diagnostic in vivo imaging data by using MRI at the preoperative stage. In addition, the pathologists can directly analyze biopsy samples during the operative and postoperative stages by using the strong scattering properties in the NIR region, even without any further need to prepare additional samples. Furthermore, the multifunctional nanostructure that was developed in this research has potential in a wider variety of novel applications that are related to modulated drug delivery, combined therapy (gene therapy and chemotherapy), and theranostic nanoplatforms.
Keyword
GoldImaging agentsMagnetic propertiesNanostructuresTargeted cancer therapy
ISSN
1439-4227
Publisher
Wiley
DOI
http://dx.doi.org/10.1002/cbic.200700416
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.