Farnesyl protein transferase inhibitory components of Lithospermum erythrorhizon

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dc.contributor.authorS J Kim-
dc.contributor.authorByoung-Mog Kwon-
dc.contributor.authorS H Kim-
dc.contributor.authorN I Baek-
dc.contributor.authorJ H Yang-
dc.contributor.authorJ J Lee-
dc.contributor.authorS I Lee-
dc.contributor.authorY E Kwon-
dc.contributor.authorH W Park-
dc.contributor.authorJ H Lee-
dc.contributor.authorJ S Park-
dc.contributor.authorD K Kim-
dc.date.accessioned2017-04-19T09:09:08Z-
dc.date.available2017-04-19T09:09:08Z-
dc.date.issued2007-
dc.identifier.issnI000-0147-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8308-
dc.description.abstractThe methanolic extract of the roots of Lithospermum erythrorhizon (Boraginaceae) was found to show inhibitory activity towards farnesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of three naphthoquinone compounds, as inhibitors of FPTase. These compounds inhibited the FPTase activity in a dose-dependent manner.-
dc.publisherKorean Society of Pharmacognosyko
dc.titleFarnesyl protein transferase inhibitory components of Lithospermum erythrorhizon-
dc.title.alternativeFarnesyl protein transferase inhibitory components of Lithospermum erythrorhizon-
dc.typeArticle-
dc.citation.titleNatural Products Sciences-
dc.citation.number4-
dc.citation.endPage331-
dc.citation.startPage328-
dc.citation.volume13-
dc.contributor.affiliatedAuthorByoung-Mog Kwon-
dc.contributor.alternativeName김성진-
dc.contributor.alternativeName권병목-
dc.contributor.alternativeName김성훈-
dc.contributor.alternativeName백남인-
dc.contributor.alternativeName양재헌-
dc.contributor.alternativeName이정주-
dc.contributor.alternativeName이사임-
dc.contributor.alternativeName권영애-
dc.contributor.alternativeName박희욱-
dc.contributor.alternativeName이재혁-
dc.contributor.alternativeName박정숙-
dc.contributor.alternativeName김대근-
dc.identifier.bibliographicCitationNatural Products Sciences, vol. 13, no. 4, pp. 328-331-
dc.subject.keywordboraginaceae-
dc.subject.keywordFPTase-
dc.subject.keywordlithospermum erythrorhizon-
dc.subject.keywordnaphthoquinone-
dc.subject.localboraginaceae-
dc.subject.localFPTase-
dc.subject.locallithospermum erythrorhizon-
dc.subject.localLithospermum erythrorhizon-
dc.subject.localnaphthoquinone-
dc.description.journalClassN-
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