Gene-set approach for expression pattern analysis = 유전자 발현 패턴 분석을 위한 유전자 세트 분석 방법

Cited 269 time in scopus
Metadata Downloads
Title
Gene-set approach for expression pattern analysis = 유전자 발현 패턴 분석을 위한 유전자 세트 분석 방법
Author(s)
Dougu Nam; Seon-Young Kim
Bibliographic Citation
Briefings in Bioinformatics, vol. 9, no. 3, pp. 189-197
Publication Year
2008
Abstract
Recently developed gene set analysis methods evaluate differential expression patterns of gene groups instead of those of individual genes. This approach especially targets gene groups whose constituents show subtle but coordinated expression changes, which might not be detected by the usual individual gene analysis. The approach has been quite successful in deriving new information from expression data, and a number of methods and tools have been developed intensively in recent years. We review those methods and currently available tools, classify them according to the statistical methods employed, and discuss their pros and cons. We also discuss several interesting extensions to the methods.
Keyword
Differential expression of genesDNA microarrayGene set analysis
ISSN
1467-5463
Publisher
Oxford Univ Press
DOI
http://dx.doi.org/10.1093/bib/bbn001
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.