Development of biologically active compounds from edible plant sources XXII : Isolation of indoles from the roots of Brassica campestris ssp rapa and their hACAT inhibitory activity = 식용식물자원으로부터 활성물질의 탐색 XXII : 순무 뿌리로부터 인돌 화합물의 분리 및 hACAT 저해 활성

Cited 0 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorM H Bang-
dc.contributor.authorD Y Lee-
dc.contributor.authorY J Oh-
dc.contributor.authorM W Han-
dc.contributor.authorH J Yang-
dc.contributor.authorH G Chung-
dc.contributor.authorTae Sook Jeong-
dc.contributor.authorK T Lee-
dc.contributor.authorM S Choi-
dc.contributor.authorN I Baek-
dc.date.accessioned2017-04-19T09:09:58Z-
dc.date.available2017-04-19T09:09:58Z-
dc.date.issued2008-
dc.identifier.issnI000-0171-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8387-
dc.description.abstractThe roots of Brassica campestris ssp rapa were extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H2O. From the EtOAc fraction, three compounds were isolated through the repeated silica gel and octadecyl silica gel (ODS) column chromatography. From the results of spectroscopic data including NMR and MS, the chemical structures of the compounds were determined as caulilexin C (1), indoleacetonitrile (2) and arvelexin (3). The arvelexin (3) has been isolated from this plant for the first time. Compounds 1, 2 and 3 showed inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) by 54.6 +/- 6.0%, 69.2 +/- 4.7% and 68.6 +/- 3.7%, and on human Acyl CoA: cholesterol transferase 2 (hACAT2) by 4.8 +/- 13.4%, 45.6 +/- 4.8%, and 39.5 +/- 4.3%, respectively, at 100 mu g/ml.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleDevelopment of biologically active compounds from edible plant sources XXII : Isolation of indoles from the roots of Brassica campestris ssp rapa and their hACAT inhibitory activity = 식용식물자원으로부터 활성물질의 탐색 XXII : 순무 뿌리로부터 인돌 화합물의 분리 및 hACAT 저해 활성-
dc.title.alternativeDevelopment of biologically active compounds from edible plant sources XXII : Isolation of indoles from the roots of Brassica campestris ssp rapa and their hACAT inhibitory activity-
dc.typeArticle-
dc.citation.titleJournal of Korean Society for Applied Biological Chemistry-
dc.citation.number1-
dc.citation.endPage69-
dc.citation.startPage65-
dc.citation.volume51-
dc.contributor.affiliatedAuthorTae Sook Jeong-
dc.contributor.alternativeName방면호-
dc.contributor.alternativeName이대영-
dc.contributor.alternativeName오영준-
dc.contributor.alternativeName한민우-
dc.contributor.alternativeName양혜정-
dc.contributor.alternativeName정해곤-
dc.contributor.alternativeName정태숙-
dc.contributor.alternativeName이경태-
dc.contributor.alternativeName최명숙-
dc.contributor.alternativeName백남인-
dc.identifier.bibliographicCitationJournal of Korean Society for Applied Biological Chemistry, vol. 51, no. 1, pp. 65-69-
dc.subject.keywordarvelexin-
dc.subject.keywordbrassica campestris ssp rapa-
dc.subject.keywordcaulilexin C-
dc.subject.keywordhACAT-
dc.subject.keywordindoleacetonitrile-
dc.subject.localarvelexin-
dc.subject.localbrassica campestris ssp rapa-
dc.subject.localBrassica campestris spp. Rapa-
dc.subject.localcaulilexin C-
dc.subject.localhACAT-
dc.subject.localHACAT-
dc.subject.localindoleacetonitrile-
dc.description.journalClassN-
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.