Recent advances in immobilization methods of antibodies on solid supports

Cited 204 time in scopus
Metadata Downloads
Title
Recent advances in immobilization methods of antibodies on solid supports
Author(s)
Yongwon Jung; Jin Young Jeong; Bong Hyun Chung
Bibliographic Citation
Analyst, vol. 133, no. 6, pp. 697-701
Publication Year
2008
Abstract
Antibody immobilization on a solid support is an essential process for the development of most immune-based assay systems. The choice of the immobilization method greatly affects antibody-antigen interactions on the assay surface. For the past several years, numerous strategies have been reported to control antibody immobilization, mainly by directing the orientation, stability, and density of bound antibodies on different assay platforms. Here we discuss recent developments in antibody immobilization methods with a particular focus on the strengths and limitations of reported approaches, and thereby provide a useful guideline for the selection of suitable antibody coupling procedures.
ISSN
0003-2654
Publisher
Royal Soc Chem
DOI
http://dx.doi.org/10.1039/b800014j
Type
Article
Appears in Collections:
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.