Cyathuscavins A, B, and C, new free radical scavengers with DNA protection activity from the Basidiomycete Cyathus stercoreus

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dc.contributor.authorH S Kang-
dc.contributor.authorK R Kim-
dc.contributor.authorE M Jun-
dc.contributor.authorS H Park-
dc.contributor.authorT S Lee-
dc.contributor.authorJ W Suh-
dc.contributor.authorJong Pyung Kim-
dc.date.accessioned2017-04-19T09:11:11Z-
dc.date.available2017-04-19T09:11:11Z-
dc.date.issued2008-
dc.identifier.issn0960894X-
dc.identifier.uri10.1016/j.bmcl.2008.05.110ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8511-
dc.description.abstractThree new polyketides, cyathuscavins A (1), B (2), and C (3) were isolated from the mycelium culture of Cyathus stercoreus. The structures of the compounds were elucidated on the basis of NMR and mass spectroscopic data. Antioxidant activities of the compounds were evaluated by the scavenging ability against ABTS+, DPPH, and superoxide anion radicals. Cyathuscavins A-C showed significant antioxidant activity comparable to those of reference antioxidants, BHA and Trolox. Cyathuscavins A-C protected supercoiled plasmid DNA from Fe2+/H2O2-induced breakage.-
dc.publisherElsevier-
dc.titleCyathuscavins A, B, and C, new free radical scavengers with DNA protection activity from the Basidiomycete Cyathus stercoreus-
dc.title.alternativeCyathuscavins A, B, and C, new free radical scavengers with DNA protection activity from the Basidiomycete Cyathus stercoreus-
dc.typeArticle-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.number14-
dc.citation.endPage4050-
dc.citation.startPage4047-
dc.citation.volume18-
dc.contributor.affiliatedAuthorJong Pyung Kim-
dc.contributor.alternativeName강학수-
dc.contributor.alternativeName김경록-
dc.contributor.alternativeName전은미-
dc.contributor.alternativeName박순혜-
dc.contributor.alternativeName이태수-
dc.contributor.alternativeName서주원-
dc.contributor.alternativeName김종평-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, vol. 18, no. 14, pp. 4047-4050-
dc.identifier.doi10.1016/j.bmcl.2008.05.110-
dc.subject.keywordCyathus stercoreus-
dc.subject.keywordDNA protection-
dc.subject.keywordFree radical scavenger-
dc.subject.keywordPolyketide-
dc.subject.localCyathus stercoreus-
dc.subject.localDNA protection-
dc.subject.localFree radical scavenger-
dc.subject.localPolyketide-
dc.description.journalClassY-
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Ochang Branch Institute > Natural Medicine Research Center > 1. Journal Articles
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