Molecular cloning of Vps26a, Vps26b, Vps29, and Vps35 and expression analysis of retromer complex in micro pig = 미니돼지 리트로머 컴플렉스 클로닝

Cited 0 time in scopus
Metadata Downloads
Title
Molecular cloning of Vps26a, Vps26b, Vps29, and Vps35 and expression analysis of retromer complex in micro pig = 미니돼지 리트로머 컴플렉스 클로닝
Author(s)
Ekyune Kim; Young-Hyun Kim; C H Ryu; Jae Woong Lee; Sang-Hyun Kim; Sang Rae Lee; Myeong Su Kim; W J Kim; J M Lim; Kyu Tae Chang
Bibliographic Citation
Reproductive & Developmental Biology, vol. 32, no. 1, pp. 65-70
Publication Year
2008
Abstract
Members of the Vps (Vacuolar protein sorting) protein family involved in the formation of the retromer complex have been discovered in a variety of species such as yeast, mouse, and human. A mammalian retromer complex is composed of Vps26, Vps29, and Vps35 proteins and plays an important role in cation.independent mannose.6. phosphate receptor retrieval from the endosome to the trans.Golgi network. In this study, we have identified the full.length sequences of the retromer components of Vps26, Vps29, and Vps35 in micro pigs. The cDNA sequences of these retromer components have been determined and the result showed there is 99% homology among the component counterparts from mouse, micro pigs, and humans. In addition, the retromer complexes formed with hetero.components were found in the brain of micro pigs. Based on above results, we suggest mammalian Vps components are well conserved in micro pigs.
Keyword
Vpsretromer complexmicro pig
ISSN
I000-0006
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > National Primate Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.