DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ekyune Kim | - |
dc.contributor.author | Jae Woong Lee | - |
dc.contributor.author | Dong Chul Baek | - |
dc.contributor.author | Sang Rae Lee | - |
dc.contributor.author | Myeong Su Kim | - |
dc.contributor.author | Sang-Hyun Kim | - |
dc.contributor.author | K Imakawa | - |
dc.contributor.author | Kyu Tae Chang | - |
dc.date.accessioned | 2017-04-19T09:11:31Z | - |
dc.date.available | 2017-04-19T09:11:31Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.uri | 10.1016/j.bbrc.2008.07.067 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8562 | - |
dc.description.abstract | A family of vacuolar protein sorting (Vps) proteins, which are components of mammalian retromer complex, has been studied in the mouse. Vps26a is known as a retromer component that plays an important role in embryonic development: however, its cell-type expression and precise role remain to be elucidated. In this study, we identified a new isoform of Vps26a, called Vps26aT, which was expressed specifically in the mouse testis. Diverse expression patterns of Vps26 variants in mouse tissues were determined by Western blot and RT-PCR analyses, and the direct interaction of Vps26aT with Vps35 was also demonstrated by immunoprecipitation and pull-down assay using antibodies raised against each Vps component. Our results revealed that the retromer complex could be formed from different Vps26 isoforms in a tissue-specific manner, resulting in more than two types of the retromer complex, including the Vps26a-Vps29-Vps35, Vps26aT-Vps29-Vps35, and Vps26b-Vps29-Vps35 complexes in mouse tissues. | - |
dc.publisher | Elsevier | - |
dc.title | Identification of novel retromer complexes in the mouse testis = 마우스 정소에서 정소특이적인 리트로마 복합체 동정 | - |
dc.title.alternative | Identification of novel retromer complexes in the mouse testis | - |
dc.type | Article | - |
dc.citation.title | Biochemical and Biophysical Research Communications | - |
dc.citation.number | 1 | - |
dc.citation.endPage | 21 | - |
dc.citation.startPage | 16 | - |
dc.citation.volume | 375 | - |
dc.contributor.affiliatedAuthor | Ekyune Kim | - |
dc.contributor.affiliatedAuthor | Jae Woong Lee | - |
dc.contributor.affiliatedAuthor | Dong Chul Baek | - |
dc.contributor.affiliatedAuthor | Sang Rae Lee | - |
dc.contributor.affiliatedAuthor | Myeong Su Kim | - |
dc.contributor.affiliatedAuthor | Sang-Hyun Kim | - |
dc.contributor.affiliatedAuthor | Kyu Tae Chang | - |
dc.contributor.alternativeName | 김익균 | - |
dc.contributor.alternativeName | 이재웅 | - |
dc.contributor.alternativeName | 백동철 | - |
dc.contributor.alternativeName | 이상래 | - |
dc.contributor.alternativeName | 김명수 | - |
dc.contributor.alternativeName | 김상현 | - |
dc.contributor.alternativeName | Imakawa | - |
dc.contributor.alternativeName | 장규태 | - |
dc.identifier.bibliographicCitation | Biochemical and Biophysical Research Communications, vol. 375, no. 1, pp. 16-21 | - |
dc.identifier.doi | 10.1016/j.bbrc.2008.07.067 | - |
dc.subject.keyword | Embryonic development | - |
dc.subject.keyword | Endosome | - |
dc.subject.keyword | Retromer complex | - |
dc.subject.keyword | Spermatogenesis | - |
dc.subject.keyword | Vacuolar protein sorting | - |
dc.subject.local | Embryonic development | - |
dc.subject.local | embryonic development | - |
dc.subject.local | Endosome | - |
dc.subject.local | Endosomes | - |
dc.subject.local | Retromer complex | - |
dc.subject.local | retromer complex | - |
dc.subject.local | Spermatogenesis | - |
dc.subject.local | spermatogenesis | - |
dc.subject.local | Vacuolar protein sorting | - |
dc.description.journalClass | Y | - |
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