DC Field | Value | Language |
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dc.contributor.author | M H Bang | - |
dc.contributor.author | J G Cho | - |
dc.contributor.author | M C Song | - |
dc.contributor.author | D Y Lee | - |
dc.contributor.author | M W Han | - |
dc.contributor.author | H G Chung | - |
dc.contributor.author | Tae Sook Jeong | - |
dc.contributor.author | K T Lee | - |
dc.contributor.author | M S Choi | - |
dc.contributor.author | N I Baek | - |
dc.date.accessioned | 2017-04-19T09:11:51Z | - |
dc.date.available | 2017-04-19T09:11:51Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | I000-0171 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8631 | - |
dc.description.abstract | The aerial parts of Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk) was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H₂O, successively. From the EtOAc fraction, three cycloartane-type triterpnoids and one ursane-type triterpenoid were isolated through the repeated silica gel, ODS and Sephadex LH-20 column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the triterpenoids were determined as wrightial (1), wrightial acetate (2), 27-norcycloart-20(21)-ene-25-al-3β-ol acetate (3) and ursolic acid (4). No report has been found for isolation of compound 3 in the literature so far, and compounds 1, 2 and 3 were the first to be isolated from Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk). Also, compound 1 showed Acyl-CoA:Cholesterol acyltransferase (hACAT-1) and hACAT-2 inhibitory activity with the IC∧50 values of 33.0 and 45.0 ㎍/ml, respectively. Compounds 2 and 3 inhibited hACAT-1 activity with the IC∧50 values of 12.0 and 16.0 ㎍/ml, respectively. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Development of biologically active compounds from edible plant sources-XXII: triterpenoids from the aerial parts of Sajabalssuk(Artemisia princeps PAMPANINI) = 식용식물자원으로부터 활성물질의 탐색-XXII. 사자발쑥의 지상부로부터 tritepenoid의 분리 | - |
dc.title.alternative | Development of biologically active compounds from edible plant sources-XXII: triterpenoids from the aerial parts of Sajabalssuk(Artemisia princeps PAMPANINI) | - |
dc.type | Article | - |
dc.citation.title | Journal of Korean Society for Applied Biological Chemistry | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 227 | - |
dc.citation.startPage | 223 | - |
dc.citation.volume | 51 | - |
dc.contributor.affiliatedAuthor | Tae Sook Jeong | - |
dc.contributor.alternativeName | 방면호 | - |
dc.contributor.alternativeName | 조진경 | - |
dc.contributor.alternativeName | 송명종 | - |
dc.contributor.alternativeName | 이대영 | - |
dc.contributor.alternativeName | 한민우 | - |
dc.contributor.alternativeName | 정해곤 | - |
dc.contributor.alternativeName | 정태숙 | - |
dc.contributor.alternativeName | 이경태 | - |
dc.contributor.alternativeName | 최명숙 | - |
dc.contributor.alternativeName | 백남인 | - |
dc.identifier.bibliographicCitation | Journal of Korean Society for Applied Biological Chemistry, vol. 51, no. 3, pp. 223-227 | - |
dc.subject.keyword | acyl-CoA:cholesterol acyltransferase (ACAT) | - |
dc.subject.keyword | artemisia princeps PAMPANINI | - |
dc.subject.keyword | sajabalssuk | - |
dc.subject.keyword | wrightial | - |
dc.subject.keyword | wrightial acetate | - |
dc.subject.keyword | 27-norcycloart-20(21)-ene-25-al-3β-ol acetate | - |
dc.subject.keyword | ursolic acid | - |
dc.subject.local | ACAT (acyl-CoA: cholesterol acyltransferase) | - |
dc.subject.local | Acyl-CoA:cholesterol acyltransferase (ACAT) | - |
dc.subject.local | cholesterol acytransferase (ACAT) | - |
dc.subject.local | Cholestrol Acyl Transferase (ACAT) | - |
dc.subject.local | Acyl CoA: cholesterol acyltransferase (ACAT) | - |
dc.subject.local | ACAT (Acyl-CoA:cholesterol acyltransferase) | - |
dc.subject.local | Acyl-CoA:cholesterol acyltransferase | - |
dc.subject.local | ACAT | - |
dc.subject.local | Acyl-CoA: cholesterol acyltransferase | - |
dc.subject.local | acyl-CoA:cholesterol acyltransferase (ACAT) | - |
dc.subject.local | Acyl-CoA: cholesterol acyltransferase (ACAT) | - |
dc.subject.local | Acyl-coenzyme A: cholesterol acyltransferase (ACAT) | - |
dc.subject.local | Cholesterol acytransferase (ACAT) | - |
dc.subject.local | cholestrol acyl transferase (ACAT) | - |
dc.subject.local | Artemisia princeps Pampanini | - |
dc.subject.local | artemisia princeps Pampanini | - |
dc.subject.local | artemisia princeps pampanini | - |
dc.subject.local | artemisia princeps PAMPANINI | - |
dc.subject.local | sajabalssuk | - |
dc.subject.local | wrightial | - |
dc.subject.local | wrightial acetate | - |
dc.subject.local | 27-norcycloart-20(21)-ene-25-al-3β-ol acetate | - |
dc.subject.local | Ursolic acid | - |
dc.subject.local | ursolic acid | - |
dc.description.journalClass | N | - |
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